Nanocrystals

70% of drug molecules face problems of poor bioavailability and instability. Nanotechnology applied to medicine can provide important progress, often by improving bioavailability and dose optimization. Researchers propose here a new formulation excipient-free and based on nanocrystals, improving biodisponibility & dose efficacy. The first indication developed for this technology is a new formulation of Etoposide, a commonly used molecule to treat several cancers, which faces those problems and usual side effects.

Applications

• Formulation of non-soluble drugs
• Solid cancers such as Lung, ovarian, colorectal, breast
• Acute myeloid leukemia

Competitive advantages

• Low toxicity
• Better biodisponibility
• Better efficiency
• Less administration
• Suitable for different galenic forms

Intellectual property

• International Patent Application in August 2019: EP2019/072873
• Priority EU 08.2018, PCT 07.2019

Keywords

Drug formulation - Excipient-free - Biodisponibility - Etoposide - Cancer